Summary
?Freshwater teleosts absorb Na+ from low-salt environments in the body as a nutrient.
Na+ is considered to be absorbed in exchange with ammonium ions. Here, we identified the molecule that mediates Na+/NH4+ exchange.
This study will contribute to elucidate the mechanism by which teleost fish adapt to freshwater, and may provide clues for understanding the acid waste system of the human kidney.
Summary
A collaborative team from the Tokyo Institute of Technology and Mayo Clinic identified a Na+/NH4+ exchanger for the first time in the gill of freshwater fish and characterized its activity. Freshwater fish absorb Na+ from low-salt environments from the gill. Approximately 70 years ago, Na+ was suggested to be absorbed in exchange with NH4+; however, ...
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